Parts of the AAV Packaging Plasmid

Your next cool experiment requires some AAV.  Where do you start? Plasmids of course! You just need three plasmids to start making the AAVs you need for your experiment:  the packaging plasmid which contains the AAV structural and packaging genes, the adenoviral helper plasmid which contains the proteins needed for the …

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STAP cell deja vu? 28 VSEL papers flagged by Bik

The stem cell field has puzzled on and off for years over a constellation of papers on purported stem cells including so-called VSEL and MUSE cells. Many of us haven’t been convinced that these are real stem cells. I see VSEL and MUSE fitting into a larger pattern of dubious stem …

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Red flags on stem cells sold for vaginal rejuvenation

An example of regenerative vaginal rejuvenation marketing. This medical approach, sometimes using stem cells, seems risky to me. Also, I found there is little evidence it works. When you read marketing terms like “stem cell treatment for sexual enhancement” or more specifically stem cells for “vaginal rejuvenation” what comes to …

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Weekly pubs & 2 stem cell clinics get bad news

Even in COVID times the FDA continues its stepped-up efforts against stem cell clinics and patients are suing clinics more too, which I cover in today’s post along with recommended stem cell research pubs. One of the papers at the top of my to-read list is on 3D chromatin in …

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