Biyoloji

Originally published Aug 3, 2017 and last updated Apr 6, 2021 by Will Arnold. Introducing NGS in 2017 for all incoming plasmids was a big change for Addgene – we had used Sanger sequencing for quality control for over ten years. Now, thanks to a generous donation by the Hirsh …

One of the most common questions I get from patients is about stem cell therapy for knees. Can it help knee arthritis and pain? Today’s post is a fact-check of where things stand today on stem cells for knee issues. What’s in this article Review of stem cell therapy for …

As part of our weekly reads I’m including one of my latest videos in our Stem Cell Channel on YouTube below. This particular video fact-checks stem cell face creams, but I’ve got quite a few more including on stem cell supplements, different kinds of stem cells and more. You might …

Cryogenic electron tomography (cryo-ET) is an imaging technique that allows reconstruction of high-resolution models of protein complexes in their near-native state. In cryo-ET, a sample (e.g. eukaryotic cells grown on an EM grid) is first vitrified, then thinned to the appropriate thickness (100-300 nm) using a Focussed Ion Beam (FIB) …

No pranks, just fun and games this April Fool’s Day on the Addgene blog.  We’ve been mostly working remotely for the last year to give our lab and shipping teams enough space at HQ and for some of us, that means spending more time with our pets. These new “co-workers” …

In the stem cell world some corporate names end up being very similar with the latest example being several companies with the name “BioLife.” Get a BioLife…name I guess BioLife is a catchy term. You’ve got life and biology in there in one name. Let’s deconstruct what’s going on out …

In EM, contrast is generated when electrons interact with the sample. However, most biological material consists of light elements such as carbon, oxygen, and nitrogen, which interact with the electron beam only sparsely. To enhance the contrast of specimens and enable room-temperature EM imaging, contrasting agents are introduced. These react …

I remember seeing a cowboy-type TV show when I was a little kid where a guy pulled into town not slinging guns but selling snake oil. He stood right up on his wagon and started pitching the wonders of what he was selling. He had some buyers pretty quick. Eventually, …

I managed to escape to do some hiking along the coast so I’m behind on my weekly reading and I’m just getting back here on The Niche. Here are some articles I’m hoping to catch up on in coming days including an interesting overview of stem cells for tooth repair. …

Cathodoluminescence can be imaged separately from other, often complementary, types of emissions, and is used for advanced investigation of material properties. One such complementary emission form is photoluminescence. But what is the difference between these two types of emissions?